For Healthcare Professionals

Clinical Care Guidelines

 

Guidelines regarding thrombosis and thrombophilia

DVT and PE Prevention and Treatment-General Guidelines

Pregnancy, VTE and thrombophilia Guidelines

Cerebral Venous Thrombosis Guidelines

Cancer and VTE Guidelines

 

 

A.  DVT and PE Prevention and Treatment - General Guidelines:


1.  ACCP 2012

Full ACCP 2012 Guidelines  (full text)

ACCP 2012 Quick Reference Guide  (This .pdf is a quick reference which lists each guideline and breaks it down by patient population, recommendation, and grade, in an easily searchable and convenient format.)

Clot Connect Summary of ACCP 2012 Guidelines related to DVT and PE. (summary)

 

ACCP Guidelines for Antithrombotic and Thrombolytic Therapy: 9th Edition

Evidence-based treatment recommendations are provided for prevention and treatment of arterial and venous thromboembolism, including in pregnant women and children, by a group of experts from the American College of Chest Physicians (ACCP),   ACCP Guidelines for Antithrombotic and Thrombolytic Therapy: 9th Edition; Chest 2012  Feb;141-2 Suppl.



2.  AHA 2011  DVT and PE 

Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis and chronic thromboembolic pulmonary hypertension. A scientific statement from the American Heart Association

Evidence-based management recommendations for iliofemoral DVT, massive and submassive PE, chronic thromboembolic pulmonary hypertension and postthrombotic syndrome are addressed in this statement by a group of experts brought together by the American Heart Association (AHA).   Jaff MR, McMurtry MS, Archer SL, et al. Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis and chronic thromboembolic pulmonary hypertension. A scientific statement from the American Heart Association. Circulation 2011,123(pre-published on the web).


3.  AAOS 2011

Full AAOS 2011 Guidelines  (full text)

Clot Connect summary of AAOS guidelines related to DVT prophylaxis  (summary)

Clinical Guideline on Prevention of Pulmonary Embolism in Patients Undergoing Total Hip or Knee Arthroplasty

Recommendations from the American Academy of Orthopedic Surgeons (AAOS) on DVT prophyalxis after orthopedic procedures.    Am Academy Ortho Surg (AAOS)  Clinical Guideline; Aug 2011

 


4. ACP 2011

ACP 2011 Guideline  (full text)

Clot Connect summary of ACP 2011 Guideline  (summary)

Clinical Guidelines:Venous Thromboembolism Prophylaxis in Hospitalized Patients: A Clinical Practice Guideline From the American College of Physicians

Recommendations from the American College of Physicians regarding prophylaxis in hospitalized patients. Amir Qaseem, Roger Chou, Linda L. Humphrey, Melissa Starkey, and Paul Shekelle for the Clinical Guidelines Committee of the American College of Physicians Ann Intern Med November 1, 2011 155:625-632



5. ASH 2011

Clinical Practice Guide on Anticoagulant Dosing and Management of Anticoagulant-Associated Bleeding Complications in Adults

The American Society of Hematology has developed a pocket-sized Quick Reference guide adapted in part from The American College of Chest Physicians Evidence-Based Clinical Practice Guideline on Antithrombotic and Thrombolytic Therapy (8th Edition).


6.  ISTH 2013

The diagnosis of symptomatic recurrent pulmonary embolism and deep vein thrombosis:  guidance from the SSC of the ISTH

The Scientific and Standardization Committee (SSC) of the International Society on Thrombosis and Haemostasis (ISTH) issued a document intended to give clinical guidance for the diagnosis of symptomatic recurrent pulmonary embolism (PE) and/or deep vein thrombosis (DVT).

 

B. Pregnancy, VTE and thrombophilia guidelines


1. ACOG 2011

Clot Connect summary of ACOG 2011 Guidelines   (summary)

Practice Bulletin 123:  Thromboembolism in Pregnancy  (full text)

Guidelines from the American College of Obstetricians and Gynecologists regarding the prevention, management and treatment of blood clots during pregnancy.  Obstetrics & Gynecology. 118(3):718-729, September 2011.  Note: journal license required to view full article

Practice Bulletin 124:  Inherited thrombophilias in Pregnancy  (full text)

Review of common thrombophilias and their association with maternal venous thromboembolism risk, adverse pregnancy outcomes, indications for screening to detect these conditions and management options during pregnancy. Obstetrics & Gynecology. 118(3):730-740, September 2011.  Note: journal license required to view full article. 

 


 

 

C.  Cerebral Venous Thrombosis Guidelines:


1. AHA 2011 Cerebral venous thrombosis

Diagnosis and Management of Cerebral Venous Thrombosis: A Statement for Health Care Professionals from the American Heart Association

This consensus statement provides a comprehensive overview of cerebral venous sinus thrombosis and provides evidence-based recommendations for its diagnosis, management, and treatment. The group of experts was brought together by the American Heart Association (AHA). Gustavo Saposnik et al. Diagnosis and Management of Cerebral Venous Thrombosis: A Statement for Healthcare Professionals; Stroke. 2011 Apr;42(4):1158-1192. Epub 2011 Feb 3.

 


 

 


 

D.  Cancer and VTE guidelines:  


1. NCCN 2013

 NCCN Clinical Practice Guidelines for Venous Thromboembolic Disease

Comprehensive. Evidence-based guidelines from the National Comprehensive Cancer Network (NCCN) covering prevention, care and management of venous thromboembolism (VTE) in cancer patients. Note: this site requires registration (free) before being able to view this document.


2. ACCP 2012 - Prevention of VTE in Cancer Patients

Prevention of VTE

Discusses the prevention of venous thromboembolism (VTE), including cancer patients, and is part of the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (9th Edition). 


3. ACCP 2012 – Treatment of VTE in Cancer patients

Antithrombotic Therapy for Venous Thromboembolic Disease

Discusses the treatment of venous thromboembolism (VTE), including cancer patients, and is part of the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (9th Edition).


4.  ASCO 2013

Venous Thromboembolism Prophylaxis and Treatment in Patients with Cancer: American Society of Clinical Oncology Practice Guideline Update

Detailed, evidence-based recommendations for the use of anticoagulation in the prevention and treatment of venous thromboembolism (VTE) in patients with cancer. Lyman GH et al.  Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update  J Clin Oncol.  May 13, 2013


5.  International Myeloma Working Group 2008 

Myeloma Prevention of thalidomide- and lenalidomide-associated thrombosis in myeloma

Recommendations for VTE Prophylaxis in Multiple Myeloma by the International Myeloma Working Group..  Palumbo A et al. Prevention of thalidomide- and lenalidomide-associated thrombosis in myeloma.. Leukemia. 2008;22:414-423.  Note: journal site license required to view full article.


6. International clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer 2013 

International clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer. Journal of Thrombosis and Haemostasis, 11: 56–70. An international consensus working group of experts was set up to develop guidelines according to an evidence-based medicine approach, using the GRADE system.


 7. International clinical practice guidelines for the treatment and prophylaxis of thrombosis associated with central venous catheters in patients with cancer 2013 

International clinical practice guidelines for the treatment and prophylaxis of thrombosis associated with central venous catheters in patients with cancer. Journal of Thrombosis and Haemostasis, 11: 71–80. An international working group of experts was set up to develop GCPG according to an evidence-based medicine approach, using the GRADE system.