For Patients


While much is known about blood clots and clotting disorders, there is still much yet to be learned.  Clinical trials are an important part of the research process.  Clinical trials help contribute to knowledge of and treatments for blood clots and clotting disorders.  Many of today's standards of treatment are based upon what was learned from clinical trials in the past.

Greater participation in clinical trials means faster answers to research questions, which can lead to better diagnosis and treatment options for persons affected by blood clots and clotting disorders.  Please consider participation in a clinical research trial near you.

Clinical trials lead to advances in the diagnosis and treatment of blood clots and clotting disorders.

Federal Registry of Clinical Trials: is a national registry of clinical trials, maintained by the US National Institutes of Health.  There are nearly 500 clinical trials related to blood clots (thrombosis) currently recruiting participants.


Clinical Trial Announcements

In addition to the clinical trials which can be accessed by visiting the federal registry, the following clot related studies studies may be of interest:

Reducing complications of clots, the ATTRACT trial:

If you or someone you know has been diagnosed with deep vein thrombosis (DVT) of the leg (thigh or pelvic veins) within the past 14 days, the ATTRACT trial may be of interest.  This NIH funded study investigates how to minimized long-term complications after a blood clot- chronic leg pain and swelling (known as post-thrombotic syndrome).  There are 45 sites in the United States enrolling in this trial.  Click here to learn more and to find a site location near you. 

What causes clots?  A family study:

It is known that in some persons the risk for blood clots (deep vein thrombosis and pulmonary embolism)  is partly inherited. Some genes that increase the risk for DVT and PE are known (e.g. factor V Leiden, the factor II 20210 mutation, protein, protein C, S and antithrombin mutations). However, it is suspected that many other and, as yet, unidentified genes also increase the risk for DVT and PE. One of the ways to discover such clotting genes is by studying families. A study is ongoing at the Mayo Clinic which investigates what genes put people at risk for clotting.  No visit is required.  Click here for more information.